The United States boasts the largest and most dynamic startup ecosystem in the world, with major hubs like Silicon Valley, New York City, and Boston. This ecosystem is characterized by a strong venture capital presence and a supportive culture for innovation and entrepreneurship. The U.S. continues to lead globally in technological innovation and startup activity, contributing significantly to economic growth and job creation.
As of 2024, the U.S. is home to approximately 77,927 startups. The startup ecosystem is supported by substantial venture capital investments, which totaled around $162.6 billion in 2022. This robust financial backing highlights the confidence investors have in the U.S. startup market, ensuring ample funding for innovation and growth.
Key strengths of the U.S. market include a highly skilled workforce, advanced technological infrastructure, and a culture that encourages risk-taking and entrepreneurship. The presence of major tech companies like Google, Apple, and Facebook fosters a collaborative environment and provides ample opportunities for startups. Additionally, the U.S. government offers support through various grants and tax incentives, such as the Small Business Innovation Research (SBIR) program.
Silicon Valley remains the epicenter of innovation, driving advancements in AI, biotechnology, fintech, and clean energy. New York City excels in finance and media, while Boston is strong in biotechnology and education-driven startups. These regions are crucial to the U.S. startup ecosystem, offering a wealth of resources, talent, and opportunities.
Cities like Austin, Denver, and Seattle are emerging as significant tech hubs. These cities provide a favorable business climate, quality of life, and are becoming attractive locations for startups and talent. The rise of remote work has further expanded opportunities for startups to access talent from various regions, contributing to the growth of these emerging hubs.
The U.S. startup market benefits from a comprehensive support system of accelerators, incubators, and co-working spaces. Programs like Techstars and Y Combinator have been instrumental in nurturing early-stage startups, providing mentorship, resources, and funding. These support systems help startups at various stages of their journey to scale and succeed.
Despite its strengths, the U.S. startup ecosystem faces challenges such as high costs of living, regulatory hurdles, and intense competition for talent. These challenges can create barriers for new startups and require strategic navigation to ensure long-term success.
The U.S. startup market features a diverse customer base and a culture that encourages innovation and entrepreneurship. The rise of remote work has expanded opportunities, allowing startups to access talent from various regions. The future outlook remains positive with continuous growth and innovation, driven by emerging technologies such as blockchain, quantum computing, and green energy.
The U.S. startup ecosystem is characterized by its resilience and adaptability. Despite challenges, the ecosystem continues to evolve, driven by a strong culture of entrepreneurship and technological advancements. This ensures the U.S. remains at the forefront of global innovation, contributing significantly to economic growth and job creation.
New York, U.S.A.
BioTech • Hardware (& Manufacturing) • A.I. (& Big Data) • HealthTech (& Fitness) • Blockchain (& Cryptos) • Robotics • Aerospace (& Defense) • DeepTech • Nanotechnology • Woman Focused
General Partner at Compound
Most Interested In
Emerging categories with some level of commercial viability. Post-science project investing
Not Interested In
- Anything related to marketing automation or adtech - Marketplaces - VR content studios
Investing in Frontier Tech @rothenberg-ventures . Previously: Researched at @cb-insights-1 & invested at Crane Partners.
Palo Alto - California, U.S.A.
HealthTech (& Fitness) • Medical Devices (& Hospital Services) • Healthcare (& Wellness) • Consumer
Investor in Computational Care
Most Interested In
Data Collective is a special seed and A fund focused on tech and deep data compute and novel creation or uses of data. I focus on health + data in all of its glorious forms.
Not Interested In
Network effects in health care. Network effects that leverages or creates very powerful, special data
New York, U.S.A.
Software (Web Marketplace Saas..) • Media • FinTech (& Financials services) • Retail (& E-Commerce) • HealthTech (& Fitness) • Gaming (& eSports) • Developer tools • Local commerce • Messaging • Healthcare (& Wellness) • Online Social • Consumer
Partner at BoxGroup
Denver - Washington - Los Angeles / Southern California - San Francisco Bay Area - New York, U.S.A. - Canada
Software (Web Marketplace Saas..) • Businesses Solutions • Retail (& E-Commerce) • CleanTech • A.I. (& Big Data) • HealthTech (& Fitness) • Cloud Services (& Infrastructure) • Aerospace (& Defense) • Mobility • Nanotechnology
Founding Partner at Unshackled Ventures
Most Interested In
Immigrant entreprenuers. We provide 3 things: Your scalable friends and family capital, full immigration support, including sponsorship and stewardship to help you succeed faster. Our goal is to make investment decisions in 3 meetings over 2 hours.
Not Interested In
Non-immigrant founders.
Founder @unshackled - Investor. Entrepreneur. Love being at the intersection of do good, do well.
Los Angeles - Toronto (Ontario) - Berkeley - San Francisco Bay Area - Boise City - Atlanta - New York - Seattle - Austin - South San Francisco - California, U.S.A. - Canada
Software (Web Marketplace Saas..) • Businesses Solutions • FinTech (& Financials services) • HealthTech (& Fitness) • Analytics • Robotics • Mobility
Investor & Entrepreneur
Entrepreneur and Investor
Most Interested In
Machine Intelligence Co-bots Market Networks in overlooked verticals AI to improve our healthcare system
Not Interested In
Consumer apps
Founder @direct-local-food, @gsquare-companies • Works at @bee-partners, @boise-angel-alliance • Studied at @stanford-university, @university-of-washington
Los Angeles - California, U.S.A.
Software (Web Marketplace Saas..) • PropTech • Businesses Solutions • IoT (& Wearables) • A.I. (& Big Data) • HealthTech (& Fitness) • Logistics (& Distribution) • Medical Devices (& Hospital Services) • Real Estate (& Construction) • Healthcare (& Wellness)
Partner at Pritzker Group Venture Capital
VC @Pritzker Group Venture Capital
San Francisco Bay Area - Palo Alto - California, U.S.A.
Software (Web Marketplace Saas..) • BioTech • Businesses Solutions • Hardware (& Manufacturing) • IoT (& Wearables) • A.I. (& Big Data) • HealthTech (& Fitness) • Advertising • Material Science • Healthcare (& Wellness) • Consumer
I am a very early stage venture capitalist and a Founder of True Ventures. I have started 3 companies as a Founder, and have been in the venture capital business since 1991. My background is mostly with early stage companies in the internet, media, mobile markets. My personal mission is to empower entrepreneurs because I believe that innovators can change the world. We started True Ventures because we felt as Founders that the traditional venture capital industry had grown too large to best serve the needs of the earliest stage entrepreneurs. At True, we have redesigned venture with the Founder as customer. Everything we do is designed to best help the early stage entrepreneur realize their dreams. We normally invest between $250,000-$2.5mm and are almost always the first investor in a company. Our deals are simple and clean and our funds are large for what we do. This means that although our initial checks are small, we are a powerful financial partner for a growing company, and we plan to invest large dollars with growth and success.I'm passionate about my kids, flying, and essentially anything outdoors. If we're meeting, be careful not to bring up airplanes, because I could spend all day talking about the wonder and beauty of flight, and we might not get much else done :).Specialties: very early stage venture capital, seed stage investing, startup advice, technology innovation, aviation
San Francisco Bay Area - California, U.S.A.
HealthTech (& Fitness) • Web Security (& Privacy) • Developer tools • Payments
Most Interested In
Infrastructural solutions that allow regulated industries (like healthcare) to scale faster. Companies will have a monetizable "application" but the core value of the company is in the infrastructure they're building that will allow them to do audacious things long term.
Not Interested In
Consumer products, hardware, consumer-facing health/wellness
San Francisco Bay Area, U.S.A.
Businesses Solutions • HealthTech (& Fitness) • Pets • Consumer
Founder & CEO at hims & hers *we’re hiring!!*
Andrew Dudum is the Founder and serves as Chief Executive Officer at Hi He is a Co-Founder and serves as Board Member at Ever AI. Andrew is a Co-Founding Partner at Atomic Labs. He also serves as a Venture Partner at Cherubic Ventures. He is a Co-founder of Everalbum and serves as its Chief Operating Officer & Chief Executive Officer. Prior to Atomic, Andrew led Product at TokBox.com, the leader in web-based communication. In 2012 TokBox was acquired by the global telecommunications company Telefonica ($TEF). While there, he launched OpenTok, the browser-based video technology now built into Mozilla's Firefox and serving 200+ million users a month. In 2008, Andrew founded LendforPeace.com, the first peer-to-peer micro-lending platform in the Middle East, serving thousands of loans to women in the Palestinian Territories, Syria and Lebanon. He is an active angel investor and advisor to over a dozen startups. He holds a Bachelor's in Management & Economics from University of Pennsylvania.
Austin - Texas, U.S.A.
FinTech (& Financials services) • CleanTech • HealthTech (& Fitness) • Impact • Healthcare (& Wellness) • Consumer
General Partner at True Wealth Ventures / NSF I-Corps National Faculty / Innovation & Strategy Consultant
Kerry Rupp serves as a General Partner at True Wealth Ventures. She is an Angel Investor.
She is a Board Member at BrainCheck. For over 20 years, she has launched, developed and startup companies and new lines of business for established fir As CEO and General Partner at DreamIt, a Top Ten US startup accelerator and early-stage venture fund, Kerry was directly involved with the launch of over 150 companies. During her 5-year tenure with DreamIt, she grew its programs to five cities, raised a $20M follow-on fund, and initiated the DreamIt Access (minority entrepreneur), DreamIt Athena (female entrepreneur), and DreamIt Health progra DreamIt companies in aggregate now have a market value of over $1B. Before DreamIt, Kerry was herself the founder of an online travel service, Holiday Golightly, which organized unique group travel excursions for women. She has also advised senior executives at Allrecipes.com, ReadersDigest, LexisNexis, Payscale, and Taleo on strategy, business development and marketing. Kerry began her career as a consultant with McKinsey and Andersen Consulting (now Accenture). In addition to consulting, Kerry serves as a mentor at Capital Factory and International Accelerator and on the advisory board of Medical Innovation Labs, a platform for commercializing innovations in the medical device field. Kerry holds an MBA from Harvard Business School and a BA in Biology from Duke University. Kerry volunteers on the leadership teams of Women@Austin, The Angel Forum, and the Austin chapters of Harvard Business School Alumni Club, Harvard Business School Alumni Angels and the DukeGEN Global Entrepreneurship Network. Kerry is also a judge or coach on many local and national start-up competitions (e.g., athenahealth, Harvard Business School, Rice University Business Plan Competition, TiE Texas, Energizing Health Houston, Texas Venture Labs, AARP Health Innovation). She is also a nationally-certified instructor for the National Science Foundation's Innovations Corps (I-Corps) program.
Boston - Massachusetts, U.S.A.
PropTech • BioTech • A.I. (& Big Data) • HealthTech (& Fitness) • Robotics • Real Estate (& Construction)
Vivjan Myrto serves as Board Member at Tranquil Data. He is a Co-Founder and serves as Managing Partner and Managing Director at Hyperplane Venture Capital. He is an Angel Investor and Board Observer at AlphaSheets. He also serves as a Board Observer at Sentenai and Indico Data Solutions.