The United states Startup Ecosystem

Overview

The United States boasts the largest and most dynamic startup ecosystem in the world, with major hubs like Silicon Valley, New York City, and Boston. This ecosystem is characterized by a strong venture capital presence and a supportive culture for innovation and entrepreneurship. The U.S. continues to lead globally in technological innovation and startup activity, contributing significantly to economic growth and job creation.

Size of the Market

As of 2024, the U.S. is home to approximately 77,927 startups. The startup ecosystem is supported by substantial venture capital investments, which totaled around $162.6 billion in 2022. This robust financial backing highlights the confidence investors have in the U.S. startup market, ensuring ample funding for innovation and growth.

Key Strengths

Key strengths of the U.S. market include a highly skilled workforce, advanced technological infrastructure, and a culture that encourages risk-taking and entrepreneurship. The presence of major tech companies like Google, Apple, and Facebook fosters a collaborative environment and provides ample opportunities for startups. Additionally, the U.S. government offers support through various grants and tax incentives, such as the Small Business Innovation Research (SBIR) program.

Major Hubs

Silicon Valley remains the epicenter of innovation, driving advancements in AI, biotechnology, fintech, and clean energy. New York City excels in finance and media, while Boston is strong in biotechnology and education-driven startups. These regions are crucial to the U.S. startup ecosystem, offering a wealth of resources, talent, and opportunities.

Emerging Hubs

Cities like Austin, Denver, and Seattle are emerging as significant tech hubs. These cities provide a favorable business climate, quality of life, and are becoming attractive locations for startups and talent. The rise of remote work has further expanded opportunities for startups to access talent from various regions, contributing to the growth of these emerging hubs.

Support Systems

The U.S. startup market benefits from a comprehensive support system of accelerators, incubators, and co-working spaces. Programs like Techstars and Y Combinator have been instrumental in nurturing early-stage startups, providing mentorship, resources, and funding. These support systems help startups at various stages of their journey to scale and succeed.

Challenges

Despite its strengths, the U.S. startup ecosystem faces challenges such as high costs of living, regulatory hurdles, and intense competition for talent. These challenges can create barriers for new startups and require strategic navigation to ensure long-term success.

Opportunities and Future Outlook

The U.S. startup market features a diverse customer base and a culture that encourages innovation and entrepreneurship. The rise of remote work has expanded opportunities, allowing startups to access talent from various regions. The future outlook remains positive with continuous growth and innovation, driven by emerging technologies such as blockchain, quantum computing, and green energy.

Resilience and Adaptability

The U.S. startup ecosystem is characterized by its resilience and adaptability. Despite challenges, the ecosystem continues to evolve, driven by a strong culture of entrepreneurship and technological advancements. This ensures the U.S. remains at the forefront of global innovation, contributing significantly to economic growth and job creation.

Angel Investment trends in the United states

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We found 3,814 VC firms in the United states investing in Material Science on Angels Partners

Alex Luce
Investing in BioTech • Hardware (& Manufactu...
 LatAm (Latin ) , San ..., U.S.A. - Canada
Investor Picture
Previous Investments
  • Picnic (Food Technology): $5000000 (Early stage VC)
  • AirWorks: $1260000 (Seed Round)
  • IOTAS, Inc.: $1000000 (Seed Round)
  • Sales Bootcamp: $600000 (Seed Round)
  • Lioness: (Early stage VC)
  • Relectrify: $9000000 (Series A)
  • OncoPrecision: $3000000 (Seed)
  • Oncoustics AI: $5000000 (Seed)
  • VenoStent: $3000000 (Seed)
  • Terra CO2: $9000000 (Seed)
  • Terra CO2 Technologies: (Seed)
  • Sepion: $2000000 (Seed)
  • Fort Robotics: (Seed)
  • Sepion Technologies: (Seed)
  • Visolis: $3400000 (Seed)

Alex Luce

LatAm (Latin ) - San Francisco Bay Area, U.S.A. - Canada

Investing In

BioTech • Hardware (& Manufacturing) • Energy • CleanTech • Food & Beverage • Material Science • Robotics • DeepTech • Mobility • Woman Focused

Description

Empowering Science Driven Founders

Parikshit Sharma
Investing in BioTech • AgroTech • Energ...
 San Francisco Bay Area, U.S.A.
Investor Picture

Parikshit Sharma

San Francisco Bay Area, U.S.A.

Investing In

BioTech • AgroTech • Energy • HealthTech (& Fitness) • Food & Beverage • Impact • Material Science • Medical Devices (& Hospital Services) • Healthcare (& Wellness) • Consumer • Pharmaceutical (& Medicine) • Woman Focused

Description

Principal at SOSV

Greg Ennis
Investing in Software (Web Marketplace Saas..) &b...
 San Francisco California, United States
Investor Picture
Previous Investments
  • BoatSetter: $2930000
  • Bumped: $14550000 (Later stage VC)
  • Redeam: (early stage)
  • SOCi, Inc.: (mid stage)
  • Particle: (mid stage)
  • Wickr: (mid stage)
  • LookingGlass Cyber Solutions, Inc.: (late stage)
  • Keyssa: (mid stage)
  • Pramata Corporation: (late stage)
  • Alianza, Inc.: (mid stage)
  • Ribbit: (early stage)
  • Perceptive Software:
  • invivodata: (mid stage)
  • Peninsula Ventures: (early stage)
  • Thompson Clive & Partners:

Greg Ennis

San Francisco California, United States

Investing In

Software (Web Marketplace Saas..) • Other • IT (& TMT) • Businesses Solutions • Hardware (& Manufacturing) • Energy • Retail (& E-Commerce) • Web Security (& Privacy) • Food & Beverage • Logistics (& Distribution) • Material Science • Aerospace (& Defense) • Mobile

Description

Co-founder and Managing Director at Peninsula Ventures

Greg Ennis is a Co-Founder and serves as Managing Director at Peninsula Ventures. Ennis serves as Operations Advisor at Naya Ventures. He is a Board Member of Lumenetix. He previously served as an Advisor at Plastc. Ennis holds an MBA from The Anderson School at UCLA and an AB in Economics and Political Science from Stanford University. Greg is also a Director and past President of the Stanford University Department of Athletics (DAPER) Investment Fund. He presently also serves as a Board Director and Observer at Net Power & Light.

Janelle Goulard
Investing in BioTech • AgroTech • Clean...
 Phoenix - Arizona, U.S.A. - Canada
Investor Picture
Previous Investments
  • Modulated Imaging: $7000000 (Series B)
  • Calysta Energy: $30000000 (Later stage VC)
  • ESS, Inc.: $13000000 (Later stage VC)
  • Airborne: $12000000 (Other)
  • Correlia Biosystems: $9570000 (Early stage VC)
  • CarbonCure Technologies: $1750000 (Later stage VC)
  • Tivra: $50000 (Early stage VC)
  • Aspect Biosystems: (Later stage VC)
  • Biodel AG: (Series A)
  • Modulim: $7000000 (Series B)

Janelle Goulard

Phoenix - Arizona, U.S.A. - Canada

Investing In

BioTech • AgroTech • CleanTech • Impact • Material Science • Medical Devices (& Hospital Services) • Woman Focused

Description

Hardtech Impact Investor

Jeb Miller
Investing in Software (Web Marketplace Saas..) &b...
 San Francisco Califor..., United States
Investor Picture
Previous Investments
  • Inkling (Publishing): $16000000
  • Volansi: $49450000 (Later stage VC)
  • Exabeam: $30000000 (Later stage VC)
  • Hound Labs: $30000000 (Later stage VC)
  • Opcity: $27000000 (Early stage VC)
  • Ripcord: $25000000 (Later stage VC)
  • Alation: $23000000 (Later stage VC)
  • Synack: $21250000 (Later stage VC)
  • Reputation.com: $20000000 (Later stage VC)
  • Thanx: $17100000 (Later stage VC)
  • Ever AI: $16000000 (Later stage VC)
  • The Muse: $16000000 (Later stage VC)
  • Rylo:
  • Rhapsody Networks:
  • Scient: (late stage)
  • Button: (mid stage)
  • Duetto: (mid stage)
  • CloudPhysics: (mid stage)
  • Origami Logic: (early stage)
  • TUNE: (mid stage)
  • Delphix: (mid stage)
  • Pertino: (early stage)
  • MoPub: (early stage)
  • FireEye: (mid stage)
  • Icon Ventures: (late stage)
  • Vuclip: (early stage)
  • World Golf Tour:
  • Ad Infuse:
  • Innotas by Planview: (early stage)
  • Pano Logic: (early stage)
  • US Department of Defense Rapid Reaction Technology Office:
  • ComVentures: (early stage)
  • TIBCO LogLogic: (early stage)
  • Intruvert Networks:
  • Worldview Technology Partners: (late stage)

Jeb Miller

San Francisco California - Palo Alto California Palo Alto, California, United States

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Media • Hardware (& Manufacturing) • Energy • Entertainment (& Sports) • CleanTech • A.I. (& Big Data) • Web Security (& Privacy) • Gaming (& eSports) • Material Science • Robotics • Real Estate (& Construction) • Mobile

Description

General Partner at Icon Ventures

Jeb Miller serves as General Partner at Icon Ventures. He was also a Board Member at Origami Logic. He is also a Board Member at Ripcord. He joined Icon Ventures in 2009, bringing over fifteen years of experience working with early-stage technology companies as a venture capitalist, operating executive and investment banker. He has relentless energy and is passionate about teaming with entrepreneurs to help build successful companies. He also serves as a consultant to the Defense Venture Catalyst Initiative program of the US Department of Defense. His venture capital career began with Morgan Stanley Technology Ventures, a corporate venture group he co-founded in 2001. He then further developed his venture investing skills with two leading venture capital firms, three years as a Partner with ComVentures and three years as a Principal with Worldview Technology Partners. Prior to joining Icon Ventures, he was with the Silicon Valley office of The Carlyle Group focused on technology investing. He also gained valuable operating experience as Managing Director of Business Development for Scient, a pioneering Internet consulting firm. He began his career with Morgan Stanley's technology investment banking groups in New York, Boston and Menlo Park. At Icon, he is on the Board of CloudPhysics, TRUSTe and WGT Sports, is a Board observer at Delphix, Inkling and Purfresh, and was involved with Devicescape, TuneIn and Vuclip. Prior Icon portfolio companies include Aster Data Systems (Teradata), FireEye (FEYE), MoPub (Twitter), Ocarina Networks (Dell) and Oodle (QVC). His past investments include AdInfuse (Velti), Innotas, IntruVert Networks (McAfee), LogLogic (TIBCO), ONStor (LSI Logic) and Rhapsody Networks (Brocade). Over the course of his twelve-year venture capital career, he has had the opportunity to work with over 40 start-ups. He has a Bachelor of Arts degree in economics from Harvard College where he graduated summa cum laude.

Brian Wallace
Investing in Software (Web Marketplace Saas..) &b...
 Westminster Colorado ..., United States
Investor Picture
Previous Investments
  • Sopris Health: $3400000
  • Ascent360: (mid stage)
  • ShapeShift.io: (early stage)
  • Shotzr: (early stage)
  • Red Canary: (mid stage)
  • Dizzion, Inc.: (mid stage)
  • Kapost: (mid stage)
  • SlamData: (early stage)
  • CommercialTribe: (early stage)
  • TaskEasy: (mid stage)
  • Pawngo:
  • Craftsy: (early stage)
  • Inspirato: (early stage)
  • NexGen Storage: (early stage)
  • SpotRight Inc.: (early stage)
  • Rebit Inc.: (mid stage)
  • TrackVia, Inc.: (early stage)
  • LogRhythm: (mid stage)
  • Access Venture Partners: (late stage)
  • Jabber, Inc.:
  • Thought Equity Motion: (early stage)

Brian Wallace

Westminster Colorado - Denver Colorado, United States

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Media • Education • Hardware (& Manufacturing) • Web Security (& Privacy) • Material Science

Description

Venture Investor

Venture Investor

Ryan Phillips
Investing in Software (Web Marketplace Saas..) &b...
 Texas , Chicago, Illi..., United States
Investor Picture
Previous Investments
  • SmartSky Networks: (Later stage VC)
  • Financial & Investment Management Group:
  • Aerotech Golf Shafts:
  • Ginger: (late stage)
  • JUST: (late stage)
  • AliveCor Inc.: (late stage)
  • Metabiota: (late stage)
  • Postmates: (mid stage)
  • WP Global Partners: (mid stage)

Ryan Phillips

Texas - Chicago, Illinois - U.S.A., United States

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Media • Education • Food & Beverage • Insurance (& InsurTech) • Logistics (& Distribution) • Material Science • Healthcare (& Wellness)

Description

Private Equity and Venture Capital Investor

Private Equity and Venture Capital Investor

Stewart Gollmer
Investing in Software (Web Marketplace Saas..) &b...
 Portola Valley, Calif..., United States
Investor Picture
Previous Investments
  • Druva: $80000000 (Later stage VC)
  • Apartment List: $60000000 (Later stage VC)
  • ResearchGate: $52600000 (Later stage VC)
  • Numerify: $27500000 (Later stage VC)
  • Lola Travel Company, Inc.: $25000000 (Later stage VC)
  • Inkling Systems: $25000000 (Later stage VC)
  • Armis Security: $17000000 (Later stage VC)
  • Plays.tv: $15000000 (Early stage VC)
  • Avere Systems: $14000000 (Later stage VC)
  • Canopy (Tax Software): $13000000 (Later stage VC)
  • Headstart: $1000000 (Seed Round)
  • Lyra Health: (mid stage)
  • Base CRM: (late stage)
  • Health Catalyst: (late stage)
  • Brighter: (early stage)
  • CareCloud: (mid stage)
  • Tealium: (mid stage)
  • SilkRoad technology: (late stage)
  • ThreatMetrix: (mid stage)
  • Cyan Optics:
  • Lucky Pai:
  • Tenaya Capital: (early stage)
  • Storwize:
  • AOptix Technologies: (late stage)
  • Cast Iron Systems:
  • Overture Networks: (late stage)
  • TeleNav: (late stage)
  • Health Language, Inc.:
  • Kodiak Networks: (early stage)
  • Navini Networks:
  • comScore, Inc.: (mid stage)
  • Lehman Brothers:

Stewart Gollmer

Portola Valley, California, United States

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Hardware (& Manufacturing) • Energy • CleanTech • Web Security (& Privacy) • Material Science • Investment Management • Mobile

Description

Managing Director at Tenaya Capital

Managing Director at Tenaya Capital

Lister Delgado
Investing in Software (Web Marketplace Saas..) &b...
 North Carolina , IDEA..., United States
Investor Picture
Previous Investments
  • Sense (Electronic Equipment and Instruments): $32110000 (Later stage VC)
  • FilterEasy: $6900000 (Later stage VC)
  • Impossible Objects: $6400000 (Early stage VC)
  • Spiffy: $5000000 (Early stage VC)
  • Payzer: $4250000 (Later stage VC)
  • Ceterus: $4200000 (Early stage VC)
  • Windsor Circle: $4103771 (Later stage VC)
  • First: $1600000 (Seed Round)
  • Klearly: $1330000 (Seed Round)
  • Pack Purchase, Inc.: (early stage)
  • Pendo.io: (early stage)
  • WedPics: (mid stage)
  • Physcient:
  • Distil Networks: (early stage)
  • GradSave: (early stage)
  • Argyle Social: (early stage)
  • Automated Insights, Inc.: (mid stage)
  • Nextray:
  • Oncoscope, Inc.:
  • IDEA Fund Partners:
  • NC IDEA: (early stage)
  • MCNC Ventures:

Lister Delgado

North Carolina - IDEA Fund Partners is a venture capital firm, United States

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Education • Material Science • Medical Devices (& Hospital Services) • Robotics • Investment Management • LegalTech • Mobile • Restaurants

Description

Managing Partner at IDEA Fund Partners

Managing Partner at IDEA Fund Partners

RyanWaddington
Investing in Energy • A.I. (& Big Data) &bul...
 Michigan, United States
Investor Picture
Previous Investments
  • Algal Scientific:
  • Arsenal Growth:
  • Deliv: (mid stage)
  • Postmates: (mid stage)
  • Sight Machine: (mid stage)
  • SkySpecs: (mid stage)
  • Sportsman Tracker: (early stage)
  • RideScout:
  • Tachyus: (early stage)
  • Root3 Technologies Inc.: (early stage)
  • FarmLogs: (early stage)
  • OptoAtmospherics:
  • Ambiq Micro: (early stage)
  • Huron River Ventures:
  • Aclaria Capital:
  • NextEnergy: (mid stage)
  • DTE Energy Ventures:
  • GetOutdoors.com:

RyanWaddington

Michigan, United States

Investing In

Energy • A.I. (& Big Data) • Material Science

Description

Founder and Partner, Huron River Ventures

Founder and Partner, Huron River Ventures

Joe Horowitz
Investing in IT (& TMT) • Media • Hardw...
 California, United States
Investor Picture
Previous Investments
  • Global Worldwide:
  • National Venture Capital Association:
  • Thanx: (mid stage)
  • TheMuse: (mid stage)
  • Area 1 Security: (early stage)
  • Synack: (early stage)
  • PLAYSTUDIOS: (mid stage)
  • TuneIn:
  • KIXEYE: (early stage)
  • Posterous (Twitter): (mid stage)
  • Sencha (IDERA):
  • Clicker Media Inc (CBS): (early stage)
  • Meebo (Google): (mid stage)
  • Ocarina Networks (Dell): (early stage)
  • Palo Alto Networks (PANW): (mid stage)
  • true[x] media (Fox): (early stage)
  • Oodle (QVC): (mid stage)
  • RedSeal Networks: (mid stage)
  • SiTime (MegaChips): (early stage)
  • FireEye, Inc. (FEYE): (early stage)
  • Avnera Corporation (Skyworks):
  • Cortina Systems (Inphi): (mid stage)
  • Mimosa Systems (Iron Mountain):
  • Proofpoint (PFPT): (mid stage)
  • Devicescape: (early stage)
  • Icon Ventures: (early stage)
  • Infinera (INFN): (early stage)
  • ICON Venture Advisors:
  • US Venture Partners:

Joe Horowitz

California, United States

Investing In

IT (& TMT) • Media • Hardware (& Manufacturing) • Energy • CleanTech • Web Security (& Privacy) • Material Science

Description

Managing General Partner at Icon Ventures

Managing General Partner at Icon Ventures

PatrickSagisi
Investing in Energy • A.I. (& Big Data) &bul...
 Menlo Park, California, United States
Investor Picture
Previous Investments
  • Heila Technologies: $70000 (Seed Round)
  • Electriphi Inc:
  • Acario Ventures / Acario Innovation:
  • DBL Partners:
  • Mapbox: (mid stage)
  • Trove: (early stage)
  • UrbanSitter: (mid stage)
  • DBL Investors:
  • Kateeva: (mid stage)
  • OPX Biotechnologies, Inc.: (mid stage)
  • Siva Power: (early stage)
  • ZincFive, Inc.: (early stage)
  • San Francisco 2012/BASOC:

PatrickSagisi

Menlo Park, California, United States

Investing In

Energy • A.I. (& Big Data) • Material Science • Robotics • Real Estate (& Construction) • Mobility

Description

New Energy & Sustainability VC

New Energy & Sustainability VC

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