The United states Startup Ecosystem

Overview

The United States boasts the largest and most dynamic startup ecosystem in the world, with major hubs like Silicon Valley, New York City, and Boston. This ecosystem is characterized by a strong venture capital presence and a supportive culture for innovation and entrepreneurship. The U.S. continues to lead globally in technological innovation and startup activity, contributing significantly to economic growth and job creation.

Size of the Market

As of 2024, the U.S. is home to approximately 77,927 startups. The startup ecosystem is supported by substantial venture capital investments, which totaled around $162.6 billion in 2022. This robust financial backing highlights the confidence investors have in the U.S. startup market, ensuring ample funding for innovation and growth.

Key Strengths

Key strengths of the U.S. market include a highly skilled workforce, advanced technological infrastructure, and a culture that encourages risk-taking and entrepreneurship. The presence of major tech companies like Google, Apple, and Facebook fosters a collaborative environment and provides ample opportunities for startups. Additionally, the U.S. government offers support through various grants and tax incentives, such as the Small Business Innovation Research (SBIR) program.

Major Hubs

Silicon Valley remains the epicenter of innovation, driving advancements in AI, biotechnology, fintech, and clean energy. New York City excels in finance and media, while Boston is strong in biotechnology and education-driven startups. These regions are crucial to the U.S. startup ecosystem, offering a wealth of resources, talent, and opportunities.

Emerging Hubs

Cities like Austin, Denver, and Seattle are emerging as significant tech hubs. These cities provide a favorable business climate, quality of life, and are becoming attractive locations for startups and talent. The rise of remote work has further expanded opportunities for startups to access talent from various regions, contributing to the growth of these emerging hubs.

Support Systems

The U.S. startup market benefits from a comprehensive support system of accelerators, incubators, and co-working spaces. Programs like Techstars and Y Combinator have been instrumental in nurturing early-stage startups, providing mentorship, resources, and funding. These support systems help startups at various stages of their journey to scale and succeed.

Challenges

Despite its strengths, the U.S. startup ecosystem faces challenges such as high costs of living, regulatory hurdles, and intense competition for talent. These challenges can create barriers for new startups and require strategic navigation to ensure long-term success.

Opportunities and Future Outlook

The U.S. startup market features a diverse customer base and a culture that encourages innovation and entrepreneurship. The rise of remote work has expanded opportunities, allowing startups to access talent from various regions. The future outlook remains positive with continuous growth and innovation, driven by emerging technologies such as blockchain, quantum computing, and green energy.

Resilience and Adaptability

The U.S. startup ecosystem is characterized by its resilience and adaptability. Despite challenges, the ecosystem continues to evolve, driven by a strong culture of entrepreneurship and technological advancements. This ensures the U.S. remains at the forefront of global innovation, contributing significantly to economic growth and job creation.

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We found 17,727 VC firms in the United states investing in HealthTech on Angels Partners

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Anna Haghgooie
Investing in HealthTech (& Fitness)
 Chicago, U.S.A.
Investor Picture
Previous Investments
  • Patientco Holdings: $27500000
  • Oncology Analytics: $21000000
  • SonarMD: (mid stage)
  • Somatus:
  • ExactCare Pharmacy: (late stage)
  • Allay Inc.:
  • Contessa Health: (early stage)
  • naviHealth, Inc.: (early stage)
  • change:healthcare, inc: (early stage)
  • Lumeris: (early stage)
  • Sandbox Industries: (mid stage)
  • Tuesday Health: $60000000 (Series A)
  • InStride Health: $26000000 (Series A)
  • Wayspring: $75000000 (Series D)
  • Wayspring: $15000000 (Series C)
  • Wayspring: $17000000 (Series B)
  • Wayspring: $8000000 (Series A)
  • Wayspring: $2000000 (Series A)
  • Wayspring: $50000 (Seed)
  • Axial Healthcare: $17000000 (Series B)
  • Axial Healthcare: $8000000 (Series A)
  • Axial Healthcare: $1800000 (Series A)
  • ZeOmega: $22000000 (Funding Round)
  • ZeOmega: $22000000 (Undisclosed)
  • NaviHealth: $4000000 (Series Unknown)
  • NaviHealth: $4100000 (Venture Round)
  • NaviHealth: (Series Unknown)
  • EveryMove: $4000000 (Series A)
  • EveryMove: $3500000 (Series A)
  • EveryMove: $3000000 (Series A)
  • EveryMove: $2600000 (Series A)

Anna Haghgooie

Chicago, U.S.A.

Investing In

HealthTech (& Fitness)

Description

Managing Director at Sandbox Industries

Managing Director at Sandbox Industries

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Brent Stone
Investing in Software (Web Marketplace Saas..) &b...
 Boston Massachusetts ..., U.S.A.
Investor Picture
Previous Investments
  • Edgile: $35000000 (Later stage VC)
  • Airband Communications Holdings: $20000000 (Later stage VC)
  • QuoVadis: $15000000 (Later stage VC)
  • V12 Data: (Later stage VC)
  • NexusTek: (Other)
  • NSM Insurance Group: (Other)
  • Thomsons Online Benefits: (Other)
  • Confie Seguros:
  • Brash Entertainment: $400000000 (Other)
  • StackPath: $180000000 (Other)
  • Accela: $143500000 (Later stage VC)

Brent Stone

Boston Massachusetts - Massachusetts, U.S.A.

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Media • Education • BioTech • Businesses Solutions • HealthTech (& Fitness) • Healthcare (& Wellness) • Investment Management

Description

Founded in 1989, ABRY Partners invests in Business Services, Communications, Education, Entertainment, Healthcare Services, Information Services, Media and Online Media. Since 1989, the firm has completed over $36 billion of leveraged transactions and other private equity investments involving approximately 450 properties. ABRY manages $3.5 billion of capital in its active funds. The firm is currently investing ABRY Partners VII, a $1.6 billion private equity fund. Investments in portfolio companies range from $25 million to $150 million, typically take controlling positions.The Senior Equity III Fund is a $750 million fund providing senior equity and mezzanine capital. Investments range from $15 million to $50 million in companies that are either owned by others, or sponsored by ABRY's private equity fund. The Senior Debt II Fund is a $1.2 billion fund providing senior debt capital to media, communications, business, and information service companies. These investments are typically first and second lien bank debt securities purchased in the primary or secondary market.

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Angela Tran
Investing in Software (Web Marketplace Saas..) &b...
 San Francisco Bay Are..., U.S.A.
Investor Picture
Previous Investments
  • Optimotive: $2000000 (Seed)
  • Bikky: $8000000 (Series A)
  • Bikky: $5000000 (Seed)
  • Moment Energy: $4000000 (Seed)
  • Replay: $6000000 (Seed)
  • Preemadonna: $6000000 (Seed)
  • DemandStar Corporation: $2000000 (Seed Round)
  • Lolli: $3000000 (Seed)
  • Lolli: $3000000 (Seed Round)
  • Lolli: $2000000 (Pre Seed)

Angela Tran

San Francisco Bay Area - California, U.S.A.

Investing In

Software (Web Marketplace Saas..) • BioTech • HealthTech (& Fitness)

Description

General Partner at Version One Ventures

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John Hawkins
Investing in Software (Web Marketplace Saas..) &b...
 San Francisco Califor..., U.S.A.
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John Hawkins

San Francisco California - Greenwich Connecticut - Houston Texas - Europe - Washington D.C - Connecticut - Middle East - Texas, U.S.A.

Investing In

Software (Web Marketplace Saas..) • IT (& TMT) • Media • Businesses Solutions • Hardware (& Manufacturing) • HealthTech (& Fitness)

Description

John Hawkins is a Managing Partner and co-founder of Generation Partners, a private equity firm that provides growth capital to technology-enabled services companies through buyout and minority equity investments. Through Generation and predecessor firms, John has 25 years of experience in private equity investing. Prior to founding Generation in 1995, John was a General Partner of Burr, Egan, Deleage & Co., a venture capital firm which he joined in 1987. At Burr, Egan, Deleage, John invested mainly in telecommunications, data communications, software, and business services companies. Prior to this, John worked in the Corporate Finance Department of Alex Brown & Sons, Inc. in San Francisco, where he advised information technology companies in the areas of financial strategy, public offerings and mergers & acquisitions. Earlier, John was a publishing research analyst covering information technology companies for Woodman, Kirkpatrick & Gilbreath an investment bank which was subsequently purchased by Hambrecht & Quist. In addition to Captivate Network, John has served on the Board of Directors of over 20 companies including: HotJobs (NASDAQ: HOTJ) – a pioneer in online recruiting; P-Com (NASDAQ: PCOM) – a communications infrastructure equipment supplier; Demand Media (NYSE: DMD) – a leading online media company; thePlatform – a developer of digital content software solutions; Agility Recovery Solutions – a leading disaster recovery provider; High End Systems – a premier manufacturer of intelligent lighting; ShopWiki – an advanced comparison shopping search engine; Donuts – a domain registry where he is a board observer; and iCrossing – a large independent, global interactive advertising agency. John graduated with a Bachelor of Arts in English with honors from Harvard College in 1982, where he was a John Harvard Scholar. John received his MBA from the Harvard Graduate School of Business in 1986. John is a member of the World Presidents’ Organization.

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Joe Raczka
Investing in Software (Web Marketplace Saas..) &b...
 New Hampshire, U.S.A.
Investor Picture
Previous Investments
  • Defendify: (mid stage)
  • VETRO FiberMap®: (mid stage)
  • York IE:
  • Hourwork: $10000000 (Series A)
  • Finmark: $6500000 (Seed Round)
  • Wunderite: $3000000 (Seed Round)
  • CloudTruth: (Seed Round)
  • Auditoria.AI: $6000000 (Venture Round)
  • Cyberhaven: $13000000 (Series A)
  • Ovation: $5000000 (Series A)
  • MedStack: $2100000 (Seed Round)
  • Datanomix: $1000000 (Seed Round)
  • WEVO: $1600000 (Angel Round)
  • Canvs: $5600000 (Series A)
  • StackShare: (Pre Seed Round)
  • Bento: $1500000 (Seed Round)
  • Metadata: (Seed Round)

Joe Raczka

New Hampshire, U.S.A.

Investing In

Software (Web Marketplace Saas..) • Businesses Solutions • HealthTech (& Fitness) • Web Security (& Privacy) • Cloud Services (& Infrastructure) • Developer tools • Woman Focused

Description

Co-Founder and Managing Partner at York IE

Co-Founder and Managing Partner at York IE

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Teddy Citrin
Investing in Businesses Solutions • HealthTe...
 New York, U.S.A.
Investor Picture
Previous Investments
  • Atom Finance: (early stage)
  • Bumble:
  • Guild Credit:
  • Tapcart: (early stage)
  • Peanut: (early stage)
  • Frame.io: (early stage)
  • Hubble Contacts: (early stage)
  • Greycroft: (late stage)
  • Kandji: $100000000 (Series C)
  • Kandji: $60000000 (Series B)
  • Kandji: $21000000 (Series A)
  • David Energy: $4000000 (Series Unknown)
  • David Energy: $2000000 (Pre Seed)
  • Zero Longevity Science: $8000000 (Series A)

Teddy Citrin

New York, U.S.A.

Investing In

Businesses Solutions • HealthTech (& Fitness) • Consumer

Description

Principal at Greycroft

VC @Greycroft Partners Previously: Product Manager @ebay // Student @ Wesleyan University

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Kenneth Schiciano
Investing in Software (Web Marketplace Saas..) &b...
 Boston Massachusetts, United States
Investor Picture
Previous Investments
  • iSentium: $1180000
  • Fincare: $5000000000 (Other)
  • Flexera Software: (Other)
  • Healix: (Other)
  • PetPeople: (Other)
  • Fisher Funds: (Other)
  • inspirED: (Other)
  • Biocomposites: (Other)
  • MRI Software: (Other)
  • Babilou: (Other)
  • Ideal Cures: (Later stage VC)
  • Tracker Corp:
  • Clearmatics: (early stage)
  • Digital Asset: (early stage)
  • Bats Global Markets, Inc.:
  • trueEX Group LLC:
  • Lava Trading:

Kenneth Schiciano

Boston Massachusetts, United States

Investing In

Software (Web Marketplace Saas..) • Other • IT (& TMT) • Businesses Solutions • FinTech (& Financials services) • Hardware (& Manufacturing) • HealthTech (& Fitness) • Insurance (& InsurTech) • Investment Management

Description

Managing Director, TA Associates

Kenneth Schiciano serves as Managing Director & Co-Head of the North America Technology Group at TA Associates Management. In addition to TierPoint, he serves on the board of directors for Arxan Technologies, Insurity, and RGM Advisors. He formerly served on the boards of Cosentry, CyOptics, Datek Online Holdings, Fractal Analytics, FTP Software, ION Investment Group, MetroPCS Communications, NetScout Systems, and The Island ECN. Prior to joining TA in 1988, he was a member of the technical staff of AT&T Bell Laboratories, as a Systems Engineer in the switching systems area. Schiciano received a BS, summa cum laude, in Electrical Engineering and Computer Science from Duke University, an MS in Electrical Engineering from Stanford University and an MS degree in Management from the Massachusetts Institute of Technology Sloan School of Management.

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Dan Williams
Investing in Software (Web Marketplace Saas..) &b...
 Illinois, United States
Investor Picture
Previous Investments
  • Arctic Wolf Networks: (late stage)
  • CloudBees: (late stage)
  • BitPay: (late stage)
  • Socrata:
  • Delta-v Capital:
  • American Capital:
  • FoxNot: (mid stage)
  • Qwant:
  • Dawex: (early stage)
  • ACN - Alliance pour la Confiance Numérique: (early stage)
  • IDnomic (formerly OpenTrust / Keynectis):

Dan Williams

Illinois, United States

Investing In

Software (Web Marketplace Saas..) • Businesses Solutions • Hardware (& Manufacturing) • HealthTech (& Fitness) • Web Security (& Privacy)

Description

Partner at Delta-v Capital

Partner at Delta-v Capital

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Sunny Dhillon
Investing in Media • Education • Busine...
 Menlo Park , San Fran..., U.S.A.
Investor Picture
Previous Investments
  • Upload: $1250000
  • Skale Harbor TrustToken:
  • Remrise: $8199999 (Early stage VC)
  • Mozart Data: $4000000 (Early stage VC)
  • Landis: $2000000 (Seed Round)
  • PortalOne: $15000000 (Seed)
  • Anomalie: $14000000 (Series A)
  • Anomalie: $5000000 (Seed)
  • Archblock: $20000000 (Initial Coin Offering)
  • Harbor: $28000000 (Corporate Round)
  • Super Evil Mega Corp: $19000000 (Series Unknown)
  • Super Evil Mega Corp: $26000000 (Series B)
  • Super Evil Mega Corp: $49000 (Seed)
  • Super Evil Mega Corp: $1000000 (Seed)
  • Drifter Entertainment: $2000000 (Seed)
  • Eonite Perception: $5000000 (Seed)
  • 8i: $14000000 (Series A)
  • Cruise: $4000000 (Seed)
  • Artillery: $3000000 (Series Unknown)

Sunny Dhillon

Menlo Park - San Francisco Bay Area - California, U.S.A.

Investing In

Media • Education • Businesses Solutions • Hardware (& Manufacturing) • Sales (& Marketing) • HealthTech (& Fitness) • Web Security (& Privacy) • Gaming (& eSports) • Advertising • Analytics • Healthcare (& Wellness) • Consumer

Description

Sunny Dhillon serves as Partner at Signia Venture Partners. He joined the Signia team in 2012 after launching his own location-based mobile startup named Barstool and investing in early stage technology companies for New World Ventures in LA and Chicago. He was previously an M&A analyst in technology investment banking at Rothschild in London, a business development manager at a venture backed spin-off of New Line Cinema, and a corporate strategist for Warner Bros.He is a mentor for various incubators in Silicon Valley and is on the board of Cents of Relief, a charity based in Connecticut that focuses on reducing human trafficking in Indian urban slums. He is also a board member for Next Gen Partners, the Valley's leading venture capital mentoring organization.Sunny invests across consumer and enterprise sector startups, with a particular interest in gaming, consumer, and digital health.Sunny graduated with his MBA from the Kellogg School of Management at Northwestern University, where he was a Lee Hague Scholar. He has an undergraduate honors degree in Economics & Management from Oxford University and a master's in International Relations & History from the London School of Economics (LSE), where he graduated with distinction. He served as Board Observer at Artillery Games. He also serves as Board Member at Drifter Entertainment. He serves as an Advisor at TheWaveVR.

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Alex Taussig
Investing in Software (Web Marketplace Saas..) &b...
 Menlo Park , San Fran..., U.S.A.
Investor Picture
Previous Investments
  • Udaan: $3240000000 (Later stage VC)
  • ShareChat: $1163100000 (Later stage VC)
  • FastFox: $300000000 (Early stage VC)
  • BYJU’S: $75000000 (Later stage VC)
  • Reflektive: $60000000 (Later stage VC)
  • Highfive: $32000000 (Later stage VC)
  • Ladder: $30000000 (Later stage VC)
  • Dremio Corporation: $25000000 (Later stage VC)
  • Arctic Wolf Networks: $16000000 (Later stage VC)
  • InnovAccer: $15600000 (Early stage VC)
  • MDClone: $10000000 (Early stage VC)
  • laiye: (Later stage VC)
  • Faire (formerly Indigo Fair): $40000000 (Series B)
  • Table22: $11000000 (Series A)
  • Yaysay: $8000000 (Seed)
  • Archive: $15000000 (Series A)
  • Muni Tienda: $20000000 (Series A)
  • Daily Harvest: $77000000 (Series D)
  • Daily Harvest: $43000000 (Series B)
  • All Day Kitchens: $65000000 (Series C)
  • Flockjay: $11000000 (Series A)
  • Flockjay: $3000000 (Seed)
  • AWA Studios: $10000000 (Series A)
  • Zola: $100000000 (Series D)
  • Zola: $25000000 (Series C)
  • Jaunt: $65000000 (Series C)
  • Jaunt: $28000000 (Series B)
  • Rethink Robotics: $20000000 (Series B)

Alex Taussig

Menlo Park - San Francisco Bay Area - California, U.S.A.

Investing In

Software (Web Marketplace Saas..) • Media • Education • Retail (& E-Commerce) • HealthTech (& Fitness) • Gaming (& eSports) • Healthcare (& Wellness) • Nanotechnology • Online Social • Consumer

Description

Partner at Lightspeed

Partner at @lightspeed-venture-partners. Investing in consumer technology startups. AB Harvard, SM MIT, MBA Harvard.

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Uri Zilberman
Investing in Software (Web Marketplace Saas..) &b...
 New York - New Jersey, U.S.A. - Israel
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Uri Zilberman

New York - New Jersey, U.S.A. - Israel

Investing In

Software (Web Marketplace Saas..) • FinTech (& Financials services) • Energy • IoT (& Wearables) • A.I. (& Big Data) • HealthTech (& Fitness) • Web Security (& Privacy) • Cloud Services (& Infrastructure) • Medical Devices (& Hospital Services) • Mobility

Description

Most Interested In

AI/ML Security Autonomous cars SaaS MedTech FinTech Any early-stage technology/idea that can have an impact....

Not Interested In

Are you an early stage team with a disruptive idea? We help founders bring ideas to life. We can lead Pre-Seed, Seed, and help through a successful A round. We tend to get more involved in B2B or B2B2C business models and look for companies in early to early-early stages.... An areas we can add the most value.

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Parul Singh
Investing in Software (Web Marketplace Saas..) &b...
 Cambridge , Massachus..., U.S.A.
Investor Picture
Previous Investments
  • Cashdrop: $11700000 (Later stage VC)
  • Shield AI: $10500000 (Early stage VC)
  • Mable (Distributors/Wholesale): $8500000 (Early stage VC)
  • SelfMade: $8000000 (Early stage VC)
  • Alyce: $5300000 (Seed Round)
  • Julia Computing, Inc.: $4600000 (Seed Round)
  • Embark Veterinary: $4500000 (Seed Round)
  • Blissfully: $3500000 (Early stage VC)
  • Elektra Labs: $2900000 (Seed Round)
  • Bedly: $2700000 (Seed Round)
  • AdHawk: $2500000 (Seed Round)
  • Lorem (Web Developing Platform): $2500000 (Seed Round)
  • Rekener Inc.: $1750000 (Seed Round)
  • Lorem Technologies: $1100000 (Seed Round)
  • Flourish: $1000000 (Seed Round)
  • Stellar Sleep: $6000000 (Seed)
  • Glass Health: $5000000 (Seed)
  • Terminal49: $7000000 (Series A)
  • Bristle: $3000000 (Seed)
  • Vibe Bio: $12000000 (Series Unknown)
  • Karuna Health: $4000000 (Seed)
  • Karuna Health: $1000000 (Seed)

Parul Singh

Cambridge - Massachusetts, U.S.A.

Investing In

Software (Web Marketplace Saas..) • HealthTech (& Fitness) • Blockchain (& Cryptos) • Analytics • Cloud Services (& Infrastructure) • Developer tools • Consumer

Description

Most Interested In

API E-Commerce Enterprise Gaming Health and Wellness Healthcare/Medtech Internet and Mobile Marketplace Productivity

Not Interested In

We are not a thesis driven firm. Show us why what you're building is a compelling opportunity for us and let's talk.

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