5AM Ventures

About The Fund

5AM Ventures is a venture capital firm that specializes in funding and building next-generation life science companies. Established in 2002 and headquartered in San Francisco, California, 5AM Ventures focuses on supporting companies that work to solve important healthcare needs through groundbreaking breakthroughs in medicine and science. They primarily invest in private therapeutic companies, especially in early-stage ventures and have a particular emphasis on Series A companies. Their investment strategy also includes allocating funds to small and mid-cap public and later-stage private biotech and life science companies through their 5AM Opportunities Strategy. Known for their hands-on approach, they often act as an extension of the operating team for the companies they invest in. This firm's 4:59 Initiative seeks to discover, incubate, and fund innovative science, partnering with academics and entrepreneurs to reach proof-of-concept data that underpins Series A Financing. Their portfolio includes a focus on biopharmaceuticals, drug delivery technologies, and life science instruments. They support various stages of company development, ranging from seed to Series B. 5AM Ventures manages $450M from 5AM Ventures VII and $300M from 5AM Opportunities II, emphasizing their significant capital-raising capability. Historically, their portfolio companies have engaged over 80,000 patients enrolled in clinical trials across more than 8,000 test sites. Their commitment to early-stage investment is underlined by the provision of financial resources, ranging from a minimum of $100,000 to a maximum of $5,000,000, with a sweet spot of $1,500,000 for investments.